It will take time to use heavy machinery to free citizens (still trapped).
The accident in the Ghotki district of the southern Sindh province occurred before dawn after the coaches of one train, the Millat Express, derailed and fell across the adjacent track, where they were hit by the Sir Syed Express, a representative of Pakistan Railways said in a statement.
An unknown number of people were still trapped in the tangled wreckage near Daharki in northern Sindh province, a railway spokesman said, adding rescue workers had called urgently for specialist equipment so they could be reached.
Divisional Transport Officer of Pakistan Railways in Sukkur division Sajjad Wagho told Xinhua that the collision took place between the Millat Express and Sir Syed Express trains in Raiti and Ubauro areas of Ghotki district.
Expressing regret over the train accident, PPP co-chairperson Asif Zardari said that the Sindh government should take concrete steps for the rescue operation whereas the federal government should pay compensation to the families of the victims.
Ghotki SSP Umar Tufail has confirmed the death toll, but has said that it may increase.
"This is a challenging task".
Rescue and relief officials were rushed to the spot.
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Heavy machinery and cutters are required for the operation, said Deputy Commissioner Usman Abdullah.
"We are also establishing a medical camp to provide medical aid to citizens", he said.
"Ordering comprehensive investigation into railway safety faultlines".
Wagho said a relief train has also reached the nearby station to shift the injured people to hospitals and help other unhurt passengers to go to another railway station to continue their journey.
At least 75 people died when a train caught fire while travelling from Karachi to Rawalpindi in October 2019.
Two information centres have been set up in the Karachi division for information about the accident, a spokesperson for the Pakistan Railways said.
On March 7, a woman was killed while 30 were injured after several coaches of the Lahore-bound Karachi Express derailed between Mando Dero and Sanghi railway stations near Rohri.
Some of the injured passengers were listed in critical condition.