'In order to get rid of this pandemic, it's important for our fellow citizens to get vaccinated, ' Bush said. "So roll up your sleeve and do your part", says Bush in the ad, which is part of the "It's Up To You" campaign.
"Michelle and I got vaccinated against COVID-19 because we know it's the best way to beat this pandemic, protect one another, and get the country back up and running again", said Obama in a tweet.
"This is our shot", Clinton is heard saying, as close-ups of him and his wife being vaccinated are shown.
Bush says he can not wait to go see his baseball team, the Texas Rangers, play in a packed stadium.
"Now it's up to you."
President Obama says the vaccine is the first step to ending the pandemic.
And the former president told the audience at CPAC earlier this month that "everybody" should get the vaccine. 'These vaccines will protect you and those you love from this risky and deadly disease'. Trump was still in office when the ex-presidents' project began in December, according to the Ad Council, and he did not attend President Joe Biden's inauguration on January 20, when Obama, Bush and Clinton gathered together in person to film.
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The second video, which runs about 30 seconds long, features only former Presidents Clinton, Bush and Obama.
The new ads are part of the Ad Council's nationwide vaccine education campaign titled "It's Up To You".
But former President Donald Trump, who got his vaccine in January, didn't want to participate.
There was no footage available of the former first couple's vaccination, added sources.
Trump has long claimed responsibility for securing a vaccine for the USA, despite his Operation Warp Speed vaccine-development program deemed a failure beset with problems and widely criticized.
Obama, 59, says he wants to be able to visit with his mother-in-law, "to hug her, and see her on her birthday".
Interviewed separately by Group SJR, POTUSes 39, 42, 43 and 44 use the PSA bully pulpit to preach in relatable terms, discussing what they plan to do now that they've been vaccinated.