Walking 100 laps of his Bedfordshire garden during the first lockdown in 2020, his story captured hearts all over the country and led to him raising an astonishing £33million for good causes attached to the health service.
"Her thoughts, and those of the Royal Family, are with them, recognising the inspiration he provided for the whole nation and others across the world".
Capt Sir Tom was awarded a knighthood from the Queen in the summer at Windsor Castle.
Speaker of the House of Commons Sir Lindsay Hoyle said: "A light has gone out in the world tonight with news of the death of our very own national treasure - Captain Sir Tom Moore".
Capt Sir Tom, as he became known in newspaper headlines and TV interviews, set out to raise 1000 pounds for the NHS by walking 100 laps but his quest went viral and caught the imagination of millions stuck at home during the first wave of the pandemic.
"In the face of this country's deepest post-war crisis, he united us all he, cheered us all up, and he embodied the triumph of the Human spirit", Johnson said.
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His daughters Hannah and Lucy have confirmed his death.
"Captain Sir Tom Moore, you gave us hope, you gave us love, you gave us smiles and joy and pride in all generations, you brought us together. We shared laughter and tears together". Above and beyond. Rest in peace'.
"Whilst he'd been in so many hearts for just a short time, he was an incredible father and grandfather, and he will stay alive in our hearts forever", his daughters said in their statement.
Labour leader Keir Starmer said: "This is incredibly sad news".
White said after a deal was struck with Sir Tom, he told the publisher he had "better get writing".
A Royal Air Force flyover was arranged as a tribute for his 100th birthday in April previous year.
He had not been vaccinated against COVID-19 because of the other medication he was taking due to pneumonia. Moore had received treatment for pneumonia over the past few weeks, his family said.
The veteran, who died aged 100 after contracting Covid-19, had become a "beacon of hope for the world" during the pandemic, the Prime Minister said.