Officials offer reassurance after AstraZeneca pause


The company also confirmed this was not the first time the trial had paused due to safety concerns.

Trials of the vaccine were already underway at different stages in Britain, the US, Brazil, South Africa and India, with others planned in Japan and Russian Federation. It was working to expedite the review to minimize any potential impact on the trial timeline. "The trial is assessing efficacy and safety of the potential vaccine in all participants, and local and systemic reactions and immune responses will be assessed in 3,000 participants", AstraZeneca wrote in a September 3 news release.

She said it's doubtful that hospitals can afford those specialized units "unless we are helping with the purchase of those very expensive refrigeration units".

Brazilian lab and hospital group DASA SA said on Wednesday it had agreed to conduct Phase 2 and 3 trials in Brazil for a COVID-19 vaccine developed by COVAXX, a unit of privately owned United Biomedical Inc.

"This is a routine action which has to happen whenever there is a potentially unexplained illness in one of the trials, while it is investigated, ensuring we maintain the integrity of the trials", a spokesperson for the British firm said.

While the developers appear to be exercising caution, the pause comes at a time when scientists are under enormous pressure to push through a COVID-19 vaccine.

140 candidate vaccines are under development across the world, 30 of which have entered the clinical trial phase.

Nightclubs, banquet halls must close again during COVID-19
Henry recommended returning to a bubble of five or six people, and maintaining distance with people outside that group. September 6 to 7 we had 107 new cases and in the last 24 hours, we have had a further 83 new cases.

Covid-19's "main gene sequence and protein level has not fundamentally changed" and the vaccine "will have no problem in dealing with these mutated viruses in the next few years and can cover them".

"In large trials, illnesses will happen by chance but must be independently reviewed to check this carefully". "The vaccine is to stop SARS-CoV-2".

The vaccine in question is one of nine that are undergoing the final phase of clinical testing, according to the World Health Organization (WHO).

"In phase three, a wider spectrum - often an older population - is usually enrolled into the vaccine [trial], which means that you will get people that may already have other susceptibilities which may not necessarily be related to the vaccine itself", Professor Plebanski told SBS News. He was briefly hospitalized and tested for COVID-19, and after his test came back negative, he learned that other participants had experienced similar side effects.

Rakova added that the volunteers will receive a second shot of the same vaccine within 21 days of the first.

Outside experts said the hold shows the systems created to ensure the safety of participants are working. The other two companies, Moderna and BioNTech, are developing vaccines using different methods than those used by AstraZeneca.

Collins expressed "cautious optimism" that one of the vaccines being tested will pan out by the end of the year but warned: "Certainly to try to predict whether it happens on a particular week before or after a particular date in early November is well beyond anything that any scientist right now could tell you".