The county has averaged about 19 new cases per day over the last 14 days, according to a 14-day moving average graph updated weekdays by the health department.
In its daily news release on Monday, the Los Angeles County Department of Public Health reported 16 deaths and 652 new cases of COVID-19-however, the numbers may be artificially low due to reporting lags that commonly occur over the weekend.
That marks a six-percent increase over a week earlier and "the highest number of reported cases in a single week since the beginning of the epidemic", the United Nations health agency said.
According to the Johns Hopkins Center for Systems Science and Engineering, the virus has infected more than 31.3 million people worldwide and killed about 965,642 people.
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72-percent of the cases have recovered.
In countries such as the United Kingdom and Spain, restrictions were announced this week in fears of another outbreak as cases surged back to levels seen earlier in the year.
The Americas, however, still account for half of all reported cases and 55 percent of global deaths. In Europe, however, the death count crossed 4,000 over a seven-day period, showing a 27 per cent increase compared to the previous period. Britain, for its part, has recorded the highest number of cumulative deaths on the continent, which stood at almost 42,000 since the pandemic began, the World Health Organization said.