"The result sucks", Leafs head coach Sheldon Keefe said.
An update on Andersen's status is expected to come after the Leafs practise early on Tuesday afternoon before they depart for NY, where they play the Rangers on Wednesday night. Nylander's goal, his 25th in a year's career, extended his streak of points to eight games (six goals, four assists), and Marner's assistants gave him five straight games with one point (goal, six assists).
'(It) can get blown out of proportion; I think it was just an honest mistake.
Andersen was replaced by Michael Hutchinson for the start of the second period.
Florida, which embarrassed Toronto 8-4 in Sunrise on January 12, weathered a Toronto surge late before Pysyk completed his hat trick into an empty net to help his team to move back into an Eastern Conference playoff spot.
Barkov's status is day-to-day after he was injured in a 4-0 loss to the Montreal Canadiens on Saturday, when he was checked in the second period by Montreal defenseman Shea Weber.
"(Andersen's) a big part of this team, obviously, but when he goes down, we've got faith in Hutch", Matthews said.
Novel coronavirus overtakes SARS as death toll in mainland China reaches 361
The San Benito couple's diagnosis is the second person-to-person transmission of the virus reported in the United States . The United Kingdom registered its first two cases on Friday in two Chinese tourists who reported feeling unwell in York.
Leafs defenceman Travis Dermott (illness) returned to the lineup after missing Saturday's 2-1 overtime win against Ottawa, while winger Kasperi Kapanen was also back following a one-game banishment to the press box for being late to Friday's practice.
Matthews is now tied with Washington's Alex Ovechkin for second place in the overall goal race, and is a back of David Pastrnak of Boston.
Of their last 29 games, the Leafs will play 14 at home where they hold a 13-7-7 record.
But Pysyk got the visitors back within one at 2:20, burying his sixth on a rebound after Hutchinson whiffed on an attempted clearance.
Replays showed Andersen and Leafs defenceman Jake Muzzin making contact also on the collision. According to Natural Stattrick, Florida had 11 scoring chances at 5v5 - including none in the second period.
Kappy has 10 goals and 18 helpers for 28 points in 52 games this season.
"If we play that kind of game 100 times, we probably win 99 of them", Keefe said.