The Bengals failed to adjust to misdirection plays throughout the contest, something the Bills have used to great effect early with Singletary.
Josh Allen has looked increasingly comfortable in his role as the Bills' starting quarterback during the team's fast start.
In addition, the Bills defense settled down after allowing NY to open the scoring on a 27-yard run by Saquon Barkley, coming up big with a pair of timely interceptions.
The 49ers had 571 yards of total offense and the Bengals couldn't stop the run (allowing 259 yards) or get their own run game going (25 yards rushing).
India BANS e-cigarettes as global backlash against vaping gathers pace
Calling E-cigarettes as "style statement" she said that people are getting into the habit of e-cigarettes as it seems cool. Around 120 million Indians smoke cigarettes or other tobacco products but the proportion of users has fallen since 2010.
Few people outside of the Bills' organization predicted Buffalo (2-0) would start the season with two wins. The Bengals come into this game with the worst rushing attack in the league despite featuring talented running back Joe Mixon in their backfield along with Giovani Bernard. Tight end is one of the stronger areas of the Bengals roster. The Bengals' defense, which looked good against the Seahawks, was physically manhandled by the San Francisco 49ers during a 41-17 loss.
The second half has been much more kind to the Bengals than the first half was Sunday.
An 0-2 start was hardly an ideal way to kick things off in Cincinnati. Meanwhile, the Bengals are looking for their first win of the season.
The Bills were a small underdog in Week 1 when they rallied in the fourth quarter to upend the Jets and at kickoff last Sunday against the Giants, had gone from a small dog to a small favorite. And on the offensive side, the Bengals have to find ways to move the ball consistently.