Kieran Tripper was repeatedly exposed by the combination of David Neres and Nicolas Tagliafico on the Tottenham right, while Victor Wanyama was a lonely figure at the back of midfield, unable to handle Ajax's unpredictable runs from deep.
"We are working closely with the stadium to take necessary action concerning the offences carried out last night and we continue to work hard to help ensure football matches remain safe and enjoyable events for all".
"After we conceded the goal, 25 to 30 minutes in, we started to be in the game".
"I think don't think at any moment they felt any pressure, any responsibility, they just went there to play the way we want to play, the way we like to play, the way we are good at, and they felt even more comfortable away from home after not very good results at home".
"The attitude was there, but we didn't find a way to play", said Pochettino. It was our fault. We still lost, but we were better in the second half.
"Second half we pushed them and tried to create chances. We knew that before".
To be at this stage of the competition with their new Tottenham Hotspur Stadium less than a month old represents what Pochettino reckons is a historic feat.
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Spurs will need Brazil global Lucas Moura to lead their assault to keep the dream alive tonight with Kane injured and Son suspended for the clash at their new stadium.
"We can not say now we were thinking about Tuesday". "We came [to London] with a winning mentality and I am really happy with how we player, but a lot of people thinl we're now in the final and there's a lot of work to be done". But we were still far from where we know we can be.
On Tuesday, Donny van de Beek gave the youthful Dutch side the win, taking Ajax to the first European Cup final in 23 years.
Vertonghen's withdrawal with a nose injury adds to Tottenham's growing list of absentees with reports that Harry Kane may be able to return in time for next week's second leg said to have been exaggerated.
Referee Antonio Mateu Lahoz made a point of asking several times whether Vertonghen was fit to carry on and got a positive answer.
Instead Sissoko was made to wait until the 39th minute to make his mark on the game when Jan Vertonghen's injury forced Pochettino into his first substitution.
But the Belgian's injury preceded a tactical change that enabled Tottenham to gain a foothold in a tie that was rapidly slipping from their grasp.