However, the designer and her husband had cashed out of her eponymous fashion empire by 2007.
Police said a housekeeper found Spade hanging from a red scarf tied to a doorknob in her bedroom.
It's not clear how long she had been dead.
"We loved Kate dearly and will miss her terribly", they said in a statement Tuesday. This is not your fault.
In the interview with the Kansas City Star newspaper via email, Kate's sister Reta Saffo helped shed light on what might have been going on with Ms. Spade, who was born Katherine Brosnahan.
On Wednesday morning, as other claims emerged that the designer's husband Andy had recently asked her for a divorce, a source close to the family shot down Saffo's remarks.
"If you put a pulse into it and every fiber of your being, people are going to respond". "She was exceedingly kind, beautifully sensitive, insanely talented, amusing as heck and one of the most generous people I have ever known".
Kate and Andy Spade sold majority stake in their company to Neiman Marcus in 1999, and the remaining shares in 2006 for a combined $93 million. Her brother-in-law, actor David Spade, tweeted a picture of her at a book signing and he said 'I love this pic of her.
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Ragland, a yoga instructor, met Queen Elizabeth II for tea with Harry and Markle at Windsor castle a day before the wedding. This isn't the first time the Queen has given such a generous wedding gift.
"She was so sharp and quick on her feet", Spade added in his tribute.
Bette Midler also shared her condolences via Twitter. I'd flown out to Napa and NYC several times in the past 3-4 years to help her to get the treatment she needed (inpatient hospitalization). Spade addressed her daughter in the note, according to two NYPD sources.
Saffor said Spade's husband and business partner Andy Spade assisted in trying to coax her into treatment.
Kate was found dead of an apparent suicide in her Manhattan apartment on Tuesday at the age of 55. She went on to win a Golden Globe for her role in the celebrated Amazon series, which made her late aunt "insanely proud". - The same apartment she reportedly took her own life in.
Grieving her sister's death, Saffo recalled "she was a dear little person".
The National Suicide Prevention Lifeline (1-800-273-8255) provides 24/7, free, confidential support for people in distress, as well as best practices for professionals and resources to aid in prevention and crisis situations.