Things began ominously for Woods, 42, when he missed the green from 94 yards after a flawless drive at the first hole, leading to a bogey.
Woods hoped to maneuver up the leaderboard after a primary spherical 73 exclusively go within the different route as a three-over-par 75 left him on four-over 148.
Years ago, Reed talked of daydreaming about making a 2-foot putt to win the Masters. Not a single par-four played under par on Friday, and the 11th was playing over half a shot harder with an average of 4.563, seeing 27 bogeys and 11 double bogeys.
"I feel like I know where I need to leave the golf ball, and most of the pins out here, and it's now just going out here and executing the game plan and staying disciplined", said Reed, who went to college at nearby Augusta State.
But he has managed just five birdies through two rounds (Reed had nine in his round Friday), has twice hit it in the water at the 12th hole, had to take an unplayable lie at the fifth on Friday and has gone nine straight major rounds shooting over par.
Every other player in the field had at least four strokes to make up on Reed, while Woods ended the day a whopping 13 shots off the pace. "I've been able to attack the golf course and not make too many mistakes".
5 birdies to the flip in 31 laid the foundations for the Ryder Cup star, however he needed to preserve his momentum to maintain an impressed Leishman, who carded a 67, at bay.
Jordan Spieth appears to be back on his game. Of course, while that might be true in the dramatic sense, you can often get a sense early of who just "has it".
Still, Woods was mostly pleased with how he's played in his first major since the 2015 PGA Championship.
"I should be fine", he said to being asked about his nerves heading into the weekend. I've played some great golf in tough conditions, whether it's wind, rain.
Reed, a five-times victor on the PGA Tour still seeking his breakthrough in a major, fired the day's lowest round, a six-under 66 that included nine birdies, to reach nine under on the week, two clear of Australian Marc Leishman (67).
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"To be able to capitalize on the par fives and make a lot of birdies there lets you be aggressive if you want to be or be cautious if you need to be", he said. Plus, he's got the temperament for the weekend at a major.
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But a small handful of others look like they have it all figured out and one looks like he's playing a different course all together.
A stunning second round 66 threw him to the top of the leaderboard, two ahead of Aussie Marc Leishman, and four clear of 2016 Open champion Henrik Stenson.
"McIlroy is three shots behind Jordan Spieth, who made five consecutive birdies on the back nine to build a two-stroke lead over Tony Finau and Matt Kuchar".
Woods was more concerned with sticking around for the weekend than chasing a green jacket. McIlroy went on to win his first major on his next try at the 2011 US Open.
Woods knows he needs a "special weekend" and some help to get back in contention.
Last month, the world number 24 had a putt to win on the final hole at the Valspar Championship in Florida, but he saw his first effort roll back to where it started, which gifted Paul Casey the title.
He was tied for the lead on two-under after eight holes but ran up a triple-bogey at the ninth after hitting a tree and ending up in a bush. He had to take an unplayable lie, but left his fourth shot through the trees in a bunker.
"It was a rough day, " Mickelson said.
Among those to miss the cut 1988 victor Sandy Lyle, defending champion Sergio Garcia and Ryder Cup hopeful Alex Noren. There are a lot of holes left.