UofL's NCAA Tournament fate now rests with the selection committee.
The Cards fell to 20-13 and will wait until Sunday night to find out if they have done enough to earn a spot in the field of 68.
Jack Wilshere says Arsenal fans deserve better after Brighton defeat
Jack Wilshere has issued a public apology to Arsenal fans after the 2-1 loss at Brighton on Sunday, saying they "deserve better". The Belgium assistant coach said on Sky Sports' Super Sunday : "Listen, I'm a competitor, you don't back down from a challenge".
After falling behind 38-21 in the first half., Louisville got 3-pointers from Dwayne Sutton and Deng Adel over the final 1:36 of the half to cut the margin to 38-27.
The first basket of the day for Louisville sub Jordan Nora left cut Virginia's lead to 56-52, the closest it had been since the opening minutes, with 8:50 left.
With the win, UVA advances to the semifinals against the victor of the Boston College/Clemson game, which was originally scheduled to tip-off at 2 p.m. Thursday. Kyle Guy, who started and played with a brace on his left knee because of a sprained medial collateral ligament he sustained last Saturday, led tournament top seed U.Va. with 19 points.