Flights from the North East will again be affected by the adverse weather today.
British Airways has suffered the most with over 300 flights being cancelled since Monday.
Delta Air Lines, the No. 2 US carrier, canceled about 750 flights Thursday night and Friday.
A statement read: "Today remains challenging and there will be disruption".
Airlines canceled some 2,542 USA flights on Friday, according to flight tracking website Flight Aware, largely on the back of the storm as rough conditions at airports from ME to Virginia hindered airlines' ability to operate smoothly.
At Durham Tees Valley Airport, meanwhile, the flights to Amsterdam scheduled for 10.10am and 4.40pm have been cancelled.
All affected customers have been notified of their options by email / SMS text message.
Ryanair plans return to full operations in all Irish airports on Saturday
At Manchester Airport, a host of domestic departures - including to Dublin, Cork, London Heathrow, Aberdeen, Edinburgh, Exeter, Southampton and Glasgow - have been cancelled, as well as a 6.15am flight to Brussels.
Yesterday (1 March) the airline was forced to cancel 40 flights due to Storm Emma's unsafe conditions.
They added: "Ryanair now plans for a return to full operations, in all Irish airports on Saturday, March 3, while remaining in close contact with the airports and the relevant authorities".
The airline says it will remain in close contact with the airports and the relevant authorities and recommends that customers check the status of their flight on the Ryanair website before making their way to the airport.
As weather conditions continue to worsen, Virgin Atlantic have not survived the "Beast from the East".
Further flights have been cancelled today, 2 March.
A late winter storm forced airlines to cancel thousands of Friday flights, as heavy rain and powerful winds swirled across the U.S. Northeast.
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