However, the 21-year-old had been a key player in recent months and came off the bench to score Barcelona's final goal in their 5-1 Champions League win over Lyon on Wednesday night.
Going into the second leg, the tie was on a knife-edge due to Barcelona's inability to score an away goal in a 0-0 draw at the Lyon Olympic Stadium.
The hosts pressed forward for more goals, but Gorgelin quickly stamped his ground to deny Messi's low shot on 42 minutes. "He was like Ronaldo". He hadn't scored since a Spanish league match in January.
The playmaker netted during the victory over Lyon in the Champions League on Wednesday night, but the alleged Manchester United target has acknowledged that his future at the Catalan giants remains unclear.
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The five-time Ballon d'Or winners have met five times in the Champions League.
The match looked comfortable at this point as Barca continued to create chances with Messi having a chip cleared off the line by Marcal.
Messi added: "There are some very good teams left like Manchester City, Juventus like I said".
Cristiano Ronaldo and Lionel Messi have both shown just why they will go down as two of the greatest players to ever step on a football pitch this week. Liverpool eliminated Bundesliga power Bayern Munich 3-1 to make the final cut.
Messi's Barca could potentially face Ronaldo's Juve in the last eight if the two sides are paired together in Friday's draw for the next round, but the Argentine would not be drawn on who they would prefer to face in the quarterfinals.