"This Withdrawal Agreement has been agreed with the UK Government, it is endorsed by leaders and is not open for renegotiation".
May urged hundreds of Conservative politicians crammed into a room inside the parliament to support another amendment that would strip out the so-called backstop plan for the Irish border, wrecking a compromise she's agreed to with the European Union in the hope of securing one with her own party.
May's "red lines", the negotiating points on which she refuses to budge, include a desire to control immigration from the EU, which means the United Kingdom can not remain in its customs union and single market.
"It is an uncomfortable thing for the European Union, as it is an uncomfortable thing for us - there are some things about it, like the fact that we would have free market access but without paying, free movement would be over, we would be out of the common agricultural policy and fisheries policy - that's not comfortable for the EU either".
Sir Graham Brady, the influential head of the Conservative Party's 1922 Committee, wants to overcome the main hurdle to May's deal by replacing the "Irish backstop".
Officials have been discussing the practicalities of implementing the Civil Contingencies Act 2004, which would allow the government to make any appropriate provisions to protect human life, health, safety and supplies, the Sunday Times said.
Brexit figurehead Boris Johnson has said he is ready to back a compromise plan to salvage Theresa May's European Union withdrawal deal.
Parliament on Tuesday will try to find some way forward by debating and voting on what changes they want May to seek to her deal.
The pound then sunk even further by almost 0.7% as a number of other amendments were voted on - particularly MPs backing a call for the Brexit deal to be passed if backstop removed.
On Monday, major supermarkets and fast-food restaurants said food supplies could be seriously disrupted.
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The proposal appears to only leave scope for the backstop to be overtaken by a better solution - of which there is no evidence of one at this point.
However Cabinet minister Damian Hinds said alternatives to the controversial backstop were already being considered.
Dominic Grieve's amendment was also voted down by 20 votes.
With two months left until Britain is due by law to leave the European Union, investors and allies have urged the British government to clinch a deal to allow an orderly exit from the club it joined in 1973.
"When will the PM understand that the ideological leaders of the ERG do not want a deal?"
Downing Street is desperate to prevent Cooper's amendment passing.
The majority of these amendments have no legal power, but if any of them receive the backing of MPs it would send a clear signal to the Government on what changes the Commons would want to see to the Withdrawal Agreement.
The amendment would have given Parliament control over the Brexit process if Theresa May fails to secure a deal by February 26.
Yvette Cooper's attempt to rule out no deal by extending Article 50 fell at the first hurdle as the House of Commons voted on a series of amendments to the prime minister's withdrawal agreement.
Sterling, which recently hit a two-and-a-half-month high of US$1.3218 on hopes that a no-deal Brexit would be avoided, fell about 0.7 per cent after lawmakers voted down efforts to prevent a no-deal exit. "I am very happy to be public about it and very happy if the Prime Minister decides I am not the right person to do the business industry job", he said, essentially daring May to sack him.