The teams have been among World Cup 2018's top scoring sides after Game 2, but their attacking prowess will fade under the pressure that accompanies this decisive game.
Japan, on four points alongside Senegal, take on Poland in Volgograd while the African team play Colombia, who have three points, in Samara.
"What I've discussed with the players is we must not waste any energy thinking whether it's better to be first or second in the group, who we might play in future rounds", said Southgate.
Harry Kane is the competition's top scorer with five goals to his name.
"We have to go out to play well in every game and to try and win every game".
As it stands it may actually prove more beneficial to finish second in the group as those who top it are on course to face Brazil in a possible quarter-final, compared to the prospect of either Switzerland or Sweden in the quarter-final for whoever finishes second. I'm not interested in what Roberto Martinez wants to do and rest a few.
"They have a brilliant opportunity first and foremost to play in a World Cup, they want to show what they can do".
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'How do you play a game not trying to win?
This is why social media is abuzz with English fans not too fussed about possibly losing to Belgium if it means they have a better chance of progressing to the semi-finals at least.
Photo Gareth Southgate wants to keep experiencing that winning feeling.
Belgium boss Roberto Martinez has made it clear he doesn't want to win and could make up to 10 changes.
"We think that we need to keep winning football matches", Southgate said.
"That´s the reality. We wanted to qualify, we´ve done that". He followed that up with a hat-trick against Panama, giving the forward the outright lead in the race for the Golden Boot ahead of Romelu Lukaku and Cristiano Ronaldo. I don't think it would be professional of us to put those players at a risk of missing the knockout phase.