Having been ineligible to play a part in the club's Champions League success, he will be even more determined to guide his side to a third European Cup title.
When Porto manager Sergio Conceicao learnt his side's fate in the first knockout round of the Champions League, there was an air of quiet optimism about the 43-year-old. "Honestly, contrary to what people say, I think this game may be one of the most balanced of the last 16 in the Champions League".
The Reds have a good record against Porto, with two wins and two draws from the four games played between the two sides. There is a cautious optimism going in to every big game Liverpool play.
The Holland global told Liverpoolfc.com: "The game will not be decided in one leg, it's over two legs".
The Round of 16 clash with the most significant African interest is FC Porto's double header with Liverpool, with the two clubs - both multi-time winners of Europe's grandest prize - able to call upon some of the continent's top players.
"On a good day we are really strong but tomorrow we need to be outstandingly strong to get a result at Porto", he said.
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Manchester United boss Jose Mourinho described his side's 1-0 defeat to Newcastle United on Sunday as "beautiful". Newcastle also thought they should have had a penalty five minutes before half-time.
No-one knows about the future.
Joking to underline his point, Klopp added: "Only because I am a friendly person I answer the question, because we are in public".
"I think Porto's also going to be hard". In his absence, Jordan Henderson is expected to return to the starting lineup in the deep-lying playmaker role.
One question is if the other eight can offer the solidity to ensure the goals the front three score are not in vain.
They have won 12 of their last 14 games, and they must have a sense of optimism ahead of the tie.
Liverpool fans are beside themselves, with a few gifs and videos of the player looking his best thrown in for good measure.
There is a huge level of respect to Porto as a club and their experience in this competition.
Until they can consistently keep clean sheets and grind out wins, the Reds may struggle to compete at the very top.